XERF
A firmer face. More defined contours. Tissues that regain their firmness and structure from within, without needles, without anaesthetic, and with no recovery time. XERF is a new multi-frequency monopolar radiofrequency technology, specifically designed for the treatment of skin laxity on the face and neck: a non-invasive approach that acts deep within the skin, stimulating the production of collagen and remodelling the tissues in a gradual and natural way. One of the most advanced technologies currently available in aesthetic medicine for those seeking tangible results without resorting to surgery.
What is XERF and how does it work?
XERF is a multi-frequency monopolar radiofrequency medical device designed for the non-invasive aesthetic dermatological treatment of sagging skin and wrinkles on the face and neck. What sets it apart from traditional radiofrequency treatments is its ability to operate at two different frequencies, allowing for the delivery of controlled energy to various tissue depths during a single session.
The operating principle is based on the conversion of RF energy into thermal energy within the tissues: the precisely generated heat stimulates fibroblasts to produce new collagen and elastin, induces a gradual contraction of the tissues and remodels the structure of the deep dermis. The result is an increase in tissue firmness, density and definition, which becomes more pronounced in the weeks following treatment.
Unlike other radiofrequency-based approaches, XERF integrates a cryogenic skin cooling system that protects the superficial layers of the skin during energy delivery, significantly improving patient comfort and reducing the risk of skin overheating.
Furthermore, the device automatically calibrates the energy output according to the area being treated, ensuring greater precision and parameter reproducibility compared to traditional systems.
XERF treatment
The key technical strength of the XERF treatment lies in the combination of two frequencies, each of which interacts with the tissues in a different way, reaching different depths and layers of the dermis:
Deep-acting effect on connective tissue
The 2 MHz frequency allows for greater penetration into the tissues, reaching the deeper layers of the dermis and the underlying connective tissue to improve tissue support and address more pronounced sagging.
Action on the mid-superficial dermis
The 6.78 MHz frequency targets the more superficial layers, improving the quality and firmness of the middle dermis, with a visible effect on skin texture and the definition of facial contours.
Integrated cryogenic cooling
The ICD (cryogenic container) system integrated into the device releases cooling gas onto the skin’s surface during treatment, protecting the epidermis from heat and ensuring a comfortable session, even in the most sensitive areas.
XERF: no needles, no anaesthesia and no need for recovery time
The XERF treatment is completely non-invasive. It does not require needles, does not involve anaesthesia and leaves no visible marks that would prevent you from resuming your normal daily activities immediately after the session. Comfort during the treatment is ensured by the integrated cryogenic cooling system, which makes the treatment well-tolerated even on the most sensitive areas of the face and neck.
The combination of deep-acting efficacy and zero recovery time is one of the factors that makes XERF particularly appealing to those seeking tangible results for skin laxity without the time commitments and risks associated with surgery or more invasive procedures.
XERF is suitable for...
Skin laxity on the face and neck
Facial and neck tissue laxity specifically the loss of tone, firmness and contour definition associated with ageing, is the primary indication for XERF. The treatment acts on the deep connective tissue, producing a firming effect that improves over time and becomes more pronounced in the weeks following treatment.
Facial wrinkles
XERF is effective against facial wrinkles by stimulating collagen renewal in the deep layers of the skin. Static wrinkles and set expression lines are gradually smoothed out, creating a natural anti-ageing effect that respects the individual features of the face.
Eye-widening effect
Targeted XERF treatment around the eyes and on the forehead lifts the eyebrows and opens up the eyes; this complements botulinum toxin treatment or is recommended as an alternative for those seeking a longer-lasting, structurally regenerative approach.
XERF: before and after - progressive and long-lasting results
XERF does not promise immediate results, and that is part of its value. The stimulation of neocollagenesis is a biological process that takes time to fully unfold: initial improvements in tissue firmness and definition become noticeable in the weeks following the first session, with the full effect typically being reached 2-3 months after the treatment cycle is completed.
The face does not undergo any artificial changes: it firms up and redefines itself, regaining the tone and density that have progressively diminished over time. It is a result that can be seen, but above all, felt: the skin is firmer, the contours are more defined, and the tissues are more toned.
Why choose Studio Garavaglia for XERF?
XERF is a technology that requires a thorough preliminary medical assessment: not all skin types respond in the same way, and not all patients are ideal candidates. At Studio Garavaglia in Milan, every treatment is assessed and carried out personally by Dr Garavaglia, who has over twenty years’ experience in advanced aesthetic medicine and the necessary dermatological expertise to select the most suitable parameters for each case.
Book a consultation
Would you like to know if XERF is the right technology for your goal?
Book a consultation at our clinic in Milan: you will receive a thorough medical assessment and all the information you need.
FAQ: frequently asked questions about XERF
What is XERF and how does it work?
XERF is a multi-frequency monopolar radiofrequency medical device designed for the non-invasive treatment of skin laxity and wrinkles on the face and neck. It uses two operating frequencies – 2 MHz and 6.78 MHz – to deliver energy to different layers of tissue, stimulating collagen production and structural remodelling of the deep dermis.
Is XERF painful?
The treatment is non-invasive and does not require anaesthesia. The integrated cryogenic cooling system protects the skin’s surface during energy delivery, making the treatment comfortable and well-tolerated even on the most sensitive areas of the face.
When can you see the results of XERF?
How many sessions are required with XERF?
How much does the XERF treatment cost in Milan?
Is XERF suitable for everyone?
Not all patients are ideal candidates for XERF. A preliminary medical assessment is essential to confirm the indication, rule out any contraindications and determine the most appropriate treatment protocol for the specific case.



