Intimate rejuvenation
Changes affecting the intimate tissues over time or as a result of hormonal changes, the menopause or pregnancy are rarely discussed with the same openness as other cosmetic concerns.
Yet vaginal dryness, discomfort, loss of tissue tone and changes to the vulvar mucosa are real, common and treatable conditions. Intimate rejuvenation with polynucleotides is a non-invasive outpatient procedure that targets the tissues of the vulvar area, improving hydration, tissue health and local function through a precise clinical approach that respects the sensitivity of the treated area.
What is vulvar rejuvenation with polynucleotides?
Vulvar rejuvenation with polynucleotides is a procedure designed to assess and treat changes in the mucosa and superficial tissues of the vulva.
Polynucleotides are biological molecules with a proven ability to stimulate fibroblasts, improve local vascularisation and restore the tissue’s extracellular matrix. Administered to the vulvar area via superficial microinjections, they act deep within the mucosa, producing a progressive and long-lasting regenerative effect.
The clinical aim of the treatment is to improve tissue quality, local hydration and mucosal function, with tangible benefits for the patient’s day-to-day comfort and quality of life.
Who is this treatment suitable for?
Intimate rejuvenation with polynucleotides is indicated for a range of clinical conditions characterised by changes in vulvar tissue quality or symptoms related to the condition of the intimate tissues:
Menopause and perimenopause
The decline in oestrogen levels that accompanies menopause and perimenopause is the most common cause of vulvovaginal atrophy: the tissues lose moisture, elasticity and thickness, leading to dryness, itching and discomfort. Treatment with polynucleotides fits into this context as a means of supporting tissue trophism, often in combination with local hormone therapies or as an alternative for those who are unable or unwilling to use them.
Oestrogen deficiency and vulvovaginal atrophy
In cases of oestrogen deficiency, regardless of age, the vulvar mucosa may show signs of atrophy, resulting in vulvar dryness, tissue fragility and symptoms of irritation. Polynucleotides work by stimulating regeneration of the extracellular matrix and improving local blood supply, producing a trophic effect that supports the restoration of tissue quality.
Discomfort and irritative symptoms
The procedure is also suitable for patients experiencing irritation, mild vulvar discomfort or dryness that is not associated with established vulvovaginal atrophy, as a first-line, non-invasive treatment to improve everyday comfort and local tissue function.
Postpartum changes and pelvic floor dysfunction
The tissue changes that occur following childbirth, together with associated pelvic floor dysfunction, may benefit from treatment with polynucleotides as part of a broader rehabilitation and regenerative programme. In such cases, Dr Garavaglia assesses whether a multidisciplinary approach is appropriate, including, where indicated, gynaecological or physiotherapy consultations.
Clinical assessment: the essential starting point
Before proceeding with treatment, Dr Garavaglia carries out a thorough clinical assessment, which includes taking a gynaecological, sexual and urological history, assessing vulvar trophism and tissue quality, and considering any endocrine, dermatological or infectious comorbidities that may influence the choice or effectiveness of treatment.
It is only following this assessment that the most appropriate treatment plan is determined: the treatment centre, the injection technique, the number of sessions and any need for related consultations in the case of more complex or persistent conditions. Where the clinical presentation warrants it, the treatment plan may be supplemented with local hormone therapy or a specialist gynaecological assessment.
How the procedure works
Vulvar rejuvenation with polynucleotides is carried out on an outpatient basis. The procedure involves superficial microinjections into the vulvar area or the vaginal vestibule, carried out by Dr Garavaglia. The treatment is generally well tolerated. During microinjections, you may experience a slight localised discomfort, which subsides quickly. No significant recovery time is required: the patient can resume her normal daily activities within a few hours of the session.
Follow-up is an integral part of the treatment process. Follow-up appointments allow your doctor to monitor the tissue response over time, assess the results achieved, and determine whether any additional treatment sessions are needed based on the progression of the clinical condition.
Results of intimate rejuvenation with polynucleotides
The results of the treatment are gradual and become more pronounced in the weeks following each session, as the polynucleotides exert their regenerative effect on the tissue. The most commonly reported benefits include improved lubrication and hydration of the mucous membranes, a reduction in dryness and everyday discomfort, a restoration of tissue elasticity and tone, and an overall improvement in the functional comfort of the intimate area.
The response to treatment varies depending on the extent of the tissue changes, the patient’s age and her hormonal status. In more complex or advanced cases, the treatment may require a greater number of sessions and an integrated approach involving other therapies.
Why choose Studio Garavaglia?
Book a consultation
Book a consultation with Dr Garavaglia at our clinic in Milan to assess your clinical condition and determine whether the treatment is suitable for your situation.